• Applicable to a broad range of drugs (over 80%)
• Pain-free, needle-free
  • Indicated for needle phobia, pain, or discomfort
  • Intended to reduce risk of needle related injuries and contamination 
  • Pain-free method for delivery of drug*  
  • Avoids gastrointestinal distress that can occur with oral delivery
  • Alternative to potentially painful dermatologic agents (e.g. liquid nitrogen)
  • Intended to reduce patient risk from powered devices, which some of our competitors use
• Opimized formulation and delivery and dosing control
  • Fast onset of action and long duration of effect*
  • Adequate drug delivery to ensure clinical effectiveness* 
  • Controlled maintenance of drug blood plasma levels after initial administration*
  • Software to prevent overdosing; fail safe controls
  • If adverse drug reactions occur, can immediately stop delivery by removing patch
  • Allows direct delivery and therefore use of lower drug doses
  • Bypasses gut absorption problems, by avoiding gut enzymes and acids
  • Allows effective use of drugs with short therapeutic windows 
• Ease of administration
  • Patch is small and compact: the size of keychain scanner card
  • Easy set up and disposal
  • No need to remember when to administer or take meds
  • Could monitor compliance, control dosing from doctor’s office
  • Maybe prescribe patch for prior application by the patient at home
  • Obviates elderly, compliance issues (e.g. dementia, difficulty swallowing pills)
  • Potential time saving benefit to hospitals for venous access, instead of needles
  • Helps with office space logistics
• Amenable to commercial manufacturing
  • More cost effective, automated/semi-automated manufacturing
  • Discrete manufacturing of patch and electronics
  • Competitors’ devices are usually expensive and complex to manufacture
  • Possible to make long-life, cost efficient electrodes
  • Thick film substrates with high definition resolution, plus special textures
  • Silver/silver chloride electrode system breaks down (i.e. “sacrificial”)
  • Cellulose nonionic derivative
  • No exotic materials or chemistries

* As demonstrated in pre-clinical studies.